Company:  ISIS PHARMACEUTICALS INC (ISIS)
Form Type:  8-K
Filing Date:  8/8/2012 
CIK:  0000874015 
Address:  2855 GAZELLE COURT 
City, State, Zip:  CARLSBAD, California 92010 
Telephone:  (760) 931-9200 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$30.93  
Change: 
0.10 (0.32%)  
Trade Time: 
10:55 AM EST  
Market Cap: 
$3.64B
Description of Business
We are the leading company in antisense drug discovery and development, exploiting a proven novel drug discovery platform we created to generate a broad pipeline of first-in-class drugs. Our strategy is to do what we do best�to discover and develop unique antisense drugs. The efficiency and broad applicability of our drug discovery platform allows us to discover and develop antisense drugs to treat a wide range of diseases, including severe and rare, cardiovascular, neurologic and metabolic diseases and cancer. The efficiency of our drug discovery technology allows us to employ a unique business strategy designed to maximize the value of our drugs and technology while maintaining an effective cost structure that limits our cash needs.
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  FORM 8-K
    SECTION 2 FINANCIAL INFORMATION
      Item 2.03. Creation of a Direct ...
    SECTION 3 SECURITIES AND TRADING MARKETS
      Item 3.02. Unregistered Sales of Equity ...
    SECTION 8 OTHER EVENTS
      Item 8.01. Other Events.
    SECTION 9 FINANCIAL STATEMENTS AND EXHIBITS
      Item 9.01. Financial Statements and ...
    SIGNATURE
    INDEX TO EXHIBITS
  EXHIBIT 99.1
  EXHIBIT 99.2
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