Company:  HELICOS BIOSCIENCES CORP (HLCS)
Form Type:  10-Q
Filing Date:  5/14/2009 
CIK:  0001274563 
Address:  ONE KENDALL SQUARE
BUILDING 700 
City, State, Zip:  CAMBRIDGE, Massachusetts 02139 
Telephone:  617-649-0540 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$1.01   		Change: 
0.01 (1.00%)  
Trade Time: 
10:03 AM EST   		Market Cap: 
$80.17M
Description of Business
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  FORM 10-Q
    Part I-Financial Information
      Item 1. Consolidated Financial Statements
        BALANCE SHEET
        INCOME STATEMENT
        CASH FLOW
        NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
      Item 2. Management's Discussion and Analysis of Financial ...
      Item 3. Quantitative and Qualitative Disclosures about ...
      Item 4. Controls and Procedures
    Part II-Other Information
      Item 1. Legal Proceedings
      Item 1A. Risk Factors
      Item 2. Unregistered Sale of Equity Securities and Use of ...
      Item 3. Defaults upon Senior Securities
      Item 4. Submission of Matters to a Vote of Security Holders
      Item 5. Other Information
      Item 6. Exhibits
    SIGNATURES
    EXHIBIT INDEX
  EXHIBIT 10.1
  EXHIBIT 31.1
    CERTIFICATION
  EXHIBIT 31.2
    CERTIFICATION
  EXHIBIT 32.1
    CERTIFICATION
BROKERAGE PARTNERS
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