Company:  EXPRESS SCRIPTS INC
Form Type:  10-K
Filing Date:  2/25/2009 
CIK:  0000885721 
Address:  ONE EXPRESS WAY 
City, State, Zip:  ST LOUIS, Missouri 63121 
Telephone:  (314) 996-0900 
Fiscal Year:  12/31 
Description of Business
Prescription drugs play a significant role in healthcare today and constitute the first line of treatment for many medical conditions. As the average age of the American population increases and pharmaceutical research enhances the potential for even more effective drugs, demand can be expected to increase. For millions of people, prescription drugs equate to the hope of improved health and quality of life. At the same time, prescription drug costs are becoming one of the most persistent challenges to healthcare affordability. Even as pharmaceutical development opens new paths to better healthcare, we confront the possibility that high costs may limit access to these therapies. Total medical costs for employers continue to outpace the rate of overall inflation.
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  FORM 10-K
    PART I
      Item 1 - Business
        NAME AND TITLE
      Item 1A-Risk Factors
      Item 1B-Unresolved Staff Comments
      Item 2 - Properties
      Item 3 - Legal Proceedings
      Item 4 - Submission of Matters to a Vote of Security Holders
    PART II
      Item 5 - Market For Registrant's Common Equity, Related ...
      Item 6 - Selected Financial Data
      Item 7 - Management's Discussion and Analysis of Financial ...
        RESULTS OF OPERATIONS
        LIQUIDITY AND CAPITAL RESOURCES
      Item 7A. - Quantitative and Qualitative Disclosures About ...
      Item 8 - Consolidated Financial Statements and Supplementary ...
        Report of Independent Registered Public Accounting Firm
        BALANCE SHEET
        INCOME STATEMENT
        STOCKHOLDERS EQUITY
        CASH FLOW
        NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
      Item 9 - Changes in and Disagreements with Accountants on ...
      Item 9A - Controls and Procedures
    PART III
      Item 10 - Directors, Executive Officers and Corporate Governance
      Item 11 - Executive Compensation
      Item 12 - Security Ownership of Certain Beneficial Owners ...
      Item 13 - Certain Relationships and Related Transactions, ...
      Item 14 - Principal Accounting Fees and Services
    PART IV
      Item 15 - Exhibits and Financial Statement Schedules
    Report of Independent Registered Public Accounting Firm
    SIGNATURES
    VALUATION AND QUALIFYING ACCOUNTS
    INDEX TO EXHIBITS
  EXHIBIT 3.1
    CERTIFICATE OF INCORPORATION
  EXHIBIT 21.1
    SUBSIDIARIES
  EXHIBIT 23.1
    CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
  EXHIBIT 31.1
  EXHIBIT 31.2
  EXHIBIT 32.1
    CERTIFICATION PURSUANT TO
  EXHIBIT 32.2
    CERTIFICATION PURSUANT TO