Company:  GENENTECH INC
Form Type:  10-Q
Filing Date:  11/4/2008 
CIK:  0000318771 
Address:  1 DNA WAY 
City, State, Zip:  SOUTH SAN FRANCISCO, California 94080 
Telephone:  650-225-1000 
Fiscal Year:  12/31 
Description of Business
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  FORM 10-Q
    PART I-FINANCIAL INFORMATION
      Item 1. Financial Statements
        INCOME STATEMENT
        CASH FLOW
        BALANCE SHEET
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
        Report of Independent Registered Public Accounting Firm
      Item 2. Management's Discussion and Analysis of Financial
      FINANCIAL STATEMENTS
        INCOME STATEMENT
      Item 3. Quantitative and Qualitative Disclosures About ...
      Item 4. Controls and Procedures
    PART II-OTHER INFORMATION
      Item 1. Legal Proceedings
      Item 1A. Risk Factors
      Item 2. Unregistered Sales of Equity Securities and Use of ...
      Item 6. Exhibits.
    SIGNATURES
  EXHIBIT 15.1
  EXHIBIT 31.1
    CERTIFICATIONS
  EXHIBIT 31.2
    CERTIFICATIONS
  EXHIBIT 32.1
    CERTIFICATIONS OF
BROKERAGE PARTNERS