Company:  ISIS PHARMACEUTICALS INC (ISIS)
Form Type:  4
Filing Date:  7/3/2012 
CIK:  0000874015 
Address:  2855 GAZELLE COURT 
City, State, Zip:  CARLSBAD, California 92010 
Telephone:  (760) 931-9200 
Fiscal Year:  12/31 
Last Trade
Last Trade: 
$20.64  
Change: 
0.25 (1.23%)  
Trade Time: 
04:00 PM EST  
Market Cap: 
$2.31B
Description of Business
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  FORM 4
    NAME AND TITLE
    NON DERIVATIVE SECURITIES
    DERIVATIVE SECURITIES
    EXPLANATIONS AND REMARKS
    REPORTING OWNERS
    SIGNATURES
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